Joined: Sep. 2008
|Sanford: A setting of 1.0 means that a single mutation can double fitness - creating as much biological functionality as the entire rest of the genome.|
I don't buy that argument either.
This is from:
J. Sanford, J. Baumgardner, W. Brewer, P. Gibson, and W. Remine. Mendel's Accountant: A biologically realistic forward-time population genetics program. SCPE. 8(2), July 2007, pp. 147-165.
|3.2. Prescribing Fitness Effects of Mutations. ...These scale factors are meaningful relative to the initial fitness value assumed for the population before we introduce new mutations. In Mendel we assume this initial fitness value to be 1.0. For deleterious mutations, since lethal mutations exist, we choose dsf del = -1.|
For favorable mutations, we allow the user to specify the (positive) scale factor dsf fav. Normally, this would be a small value (e.g., 0.01 to 0.1), since it is only in very special situations that a single beneficial mutation would
have a very large effect.
Seems to me that if the scale factor for deleterious mutations of -1 represents lethality, (i.e. no chance of reproduction), then it's inverse for beneficial mutations, +1, would represent guaranteed reproductive success, not "doubling of fitness".
The majority of the stupid is invincible and guaranteed for all time. The terror of their tyranny is alleviated by their lack of consistency. -A. Einstein (H/T, JAD)
If evolution is true, you could not know that it's true because your brain is nothing but chemicals. ?Think about that. -K. Hovind