dvunkannon
Posts: 1377
Joined: June 2008
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One pot OOL synthesis - formamide to RNA
The money shot:
| Quote | | The production in the same chemical frame of acyclonucleotides (Saladino et al. 2003), the abiotic phosphorylation of nucleosides to yield cyclic nucleotides (Costanzo et al. 2007), their nonenzymatic polymerization to yield long RNA chains (Costanzo et al. 2009), and the non-enzymatic terminal ligation of oligomers (Pino et al. 2008; Costanzo et al. 2009) show that the whole series of events leading from a one-carbon atom precursor (NH2COH) to RNA polymers may be accomplished within a single chemical frame. |
Big shout out of thanks to NASA for the virtual OOL workshop (read about it on PT). Many fantastic lectures available online.
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I’m referring to evolution, not changes in allele frequencies. - Cornelius Hunter
I’m not an evolutionist, I’m a change in allele frequentist! - Nakashima
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