dvunkannon
Posts: 1377 Joined: June 2008
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Article on a protein that mutates quickly and drives speciation.
Quote | It’s logical then to ask what specifies or controls hotspot location. Scientists have gathered evidence that three different mechanisms are involved in controlling location and activity. First, the genomic sequence around each hotspot seems to be important; for example, 40 percent of human hotspots are associated with a repeating 13-basepair motif. However, because only a portion of hotspots correlates with a specific sequence, other factors must be involved. For example, evidence is accumulating that hotspot locations are associated with certain histone modifications. The third proposed mechanism implies that a soluble factor or protein must control the location and distribution of hotspots.
Remarkably, a single protein appears to satisfy all three conditions.
Read more: Sticky fingers - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/article/display/57466/#ixzz0qwWLH2d2
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-------------- I’m referring to evolution, not changes in allele frequencies. - Cornelius Hunter
I’m not an evolutionist, I’m a change in allele frequentist! - Nakashima
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