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| Bioessays 1999 May;21(5):432-9 Generation of evolutionary novelty by functional shift. Ganfornina MD, Sanchez D. Biology Department, University of Utah, Salt Lake City 84112, USA. lazarillo@bioscience.utah.edu That biological features may change their function during evolution has long been recognized. Particularly, the acquisition of new functions by molecules involved in developmental pathways is suspected to cause important morphologic novelties. However, the current terminology describing functional changes during evolution (co-option or recruitment) fails to recognize important biologic distinctions between diverse evolutionary routes involving functional shifts. The main goal of our work is to stress the importance of an apparently trivial distinction: Whether or not the element that adopts a new function (anything from a morphologic structure to a protein domain) is a single or a duplicated element. We propose that natural selection must act in a radically different way, depending on the historic succession of co-option and duplication events; that is, co-option may provide the selective pressure for a subsequent gene duplication or could be a stabilizing factor that helps maintain redundancy after gene duplication. We review the evidence available on functional changes, focusing whenever possible on developmental molecules, and we propose a conceptual framework for the study of functional shifts during evolution with a level of resolution appropriate to the power of our current methodologies. |
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1: Ganfornina MD, Sanchez D. Related Articles, Links Generation of evolutionary novelty by functional shift. Bioessays. 1999 May;21(5):432-9. Review. PMID: 10376014 [PubMed - indexed for MEDLINE] 2: True JR, Carroll SB. Related Articles, Links Gene co-option in physiological and morphological evolution. Annu Rev Cell Dev Biol. 2002;18:53-80. PMID: 12142278 [PubMed - in process] 3: Van de Peer Y, Taylor JS, Braasch I, Meyer A. Related Articles, Links The ghost of selection past: rates of evolution and functional divergence of anciently duplicated genes. J Mol Evol. 2001 Oct-Nov;53(4-5):436-46. PMID: 11675603 [PubMed - indexed for MEDLINE] 4: Eizinger A, Jungblut B, Sommer RJ. Related Articles, Links Evolutionary change in the functional specificity of genes. Trends Genet. 1999 May;15(5):197-202. Review. PMID: 10322487 [PubMed - indexed for MEDLINE] 5: Taylor JS, Van de Peer Y, Meyer A. Related Articles, Links Genome duplication, divergent resolution and speciation. Trends Genet. 2001 Jun;17(6):299-301. Review. PMID: 11377777 [PubMed - indexed for MEDLINE] 6: Thornton JW, DeSalle R. Related Articles, Links Gene family evolution and homology: genomics meets phylogenetics. Annu Rev Genomics Hum Genet. 2000;1:41-73. Review. PMID: 11701624 [PubMed - indexed for MEDLINE] 7: Otto SP, Yong P. Related Articles, Links The evolution of gene duplicates. Adv Genet. 2002;46:451-83. Review. PMID: 11931235 [PubMed - indexed for MEDLINE] 8: Krakauer DC, Nowak MA. Related Articles, Links Evolutionary preservation of redundant duplicated genes. Semin Cell Dev Biol. 1999 Oct;10(5):555-9. Review. PMID: 10597640 [PubMed - indexed for MEDLINE] 9: Kondrashov FA, Rogozin IB, Wolf YI, Koonin EV. Related Articles, Links Selection in the evolution of gene duplications. Genome Biol. 2002;3(2):RESEARCH0008. PMID: 11864370 [PubMed - indexed for MEDLINE] [etc.] |
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1: Woolhouse ME, Webster JP, Domingo E, Charlesworth B, Levin BR. Related Articles, Links Biological and biomedical implications of the co-evolution of pathogens and their hosts. Nat Genet. 2002 Dec;32(4):569-77. PMID: 12457190 [PubMed - in process] 2: Manley GA. Related Articles, Links Evolution of structure and function of the hearing organ of lizards. J Neurobiol. 2002 Nov 5;53(2):202-11. Review. PMID: 12382276 [PubMed - in process] 3: Prince VE, Pickett FB. Related Articles, Links Splitting pairs: the diverging fates of duplicated genes. Nat Rev Genet. 2002 Nov;3(11):827-37. PMID: 12415313 [PubMed - in process] 4: Karev GP, Wolf YI, Rzhetsky AY, Berezovskaya FS, Koonin EV. Related Articles, Links Birth and death of protein domains: A simple model of evolution explains power law behavior. BMC Evol Biol. 2002 Oct 14 [epub ahead of print] PMID: 12379152 [PubMed - as supplied by publisher] [etc.] |
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(Go to http://groups.google.com/ ) find the desired thread view thread find the desired post view this message alone then the unique message ID will be displayed at the top of the message. It will be something like 20021231093815.02096.00000093@mb-cl.aol.com You must store the google groups prefix in a convinient place. It is: http://groups.google.com/groups?&selm= Next, append the ID to the prefix: (be sure you don't leave a space after the '='. http://groups.google.com/groups?....aol.com Voila! Dunk |