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  Topic: The Biologic Institute Thread, The DI's top secret lab, revealed!< Next Oldest | Next Newest >  
JohnW



Posts: 2838
Joined: Aug. 2006

(Permalink) Posted: June 27 2013,10:47   

Quote (OgreMkV @ June 27 2013,06:18)
 
Quote (Merc @ June 27 2013,06:40)
Fun!

Even when they "do science" they scramble around for a spin.

Any reasonable person would just say, "well, yeah, I guess it is pretty easy to do, sorry for the confusion".

more please

The money shot:
Quote
It was surprisingly easy to add a new function based on our knowledge of evolutionary relationships between entire protein families.

It's hard to do lab work with a bible in one hand.

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Math is just a language of reality. Its a waste of time to know it. - Robert Byers

There isn't any probability that the letter d is in the word "mathematics"...  The correct answer would be "not even 0" - JoeG

  
Dr.GH



Posts: 2138
Joined: May 2002

(Permalink) Posted: June 27 2013,10:49   

You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Edited by Dr.GH on June 27 2013,08:53

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"Science is the horse that pulls the cart of philosophy."

L. Susskind, 2004 "SMOLIN VS. SUSSKIND: THE ANTHROPIC PRINCIPLE"

   
Jim_Wynne



Posts: 1199
Joined: June 2006

(Permalink) Posted: June 27 2013,12:25   

Quote (Dr.GH @ June 27 2013,10:49)
You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Me too.  :p

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Evolution is not about laws but about randomness on happanchance.--Robert Byers, at PT

  
OgreMkV



Posts: 3654
Joined: Oct. 2009

(Permalink) Posted: June 27 2013,12:35   

Quote (Jim_Wynne @ June 27 2013,12:25)
Quote (Dr.GH @ June 27 2013,10:49)
You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Me too. :p

Me 3.

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Ignored by those who can't provide evidence for their claims.

http://skepticink.com/smilodo....retreat

   
Lou FCD



Posts: 5402
Joined: Jan. 2006

(Permalink) Posted: June 27 2013,18:30   

Quote (OgreMkV @ June 27 2013,13:35)
Quote (Jim_Wynne @ June 27 2013,12:25)
 
Quote (Dr.GH @ June 27 2013,10:49)
You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Me too. :p

Me 3.

I quoted JohnW.


Making Fun of the Biologic Institute by Lou FCD, on Flickr

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Lou FCD is still in school, so we should only count him as a baby biologist. -carlsonjok -deprecated
I think I might love you. Don't tell Deadman -Wolfhound

Work-friendly photography
NSFW photography

   
Doc Bill



Posts: 1039
Joined: April 2007

(Permalink) Posted: June 27 2013,19:15   

I'd make a suitably inappropriate comment on their Facebook site but, of course, I'm blocked.

Yes, Gauger's silver banhammer came down on my head.

  
Merc



Posts: 5
Joined: June 2013

(Permalink) Posted: June 27 2013,20:16   

The sad thing is that I've done far more to test her hypothesis than she has--inadvertently, with a completely different goal.

Would someone like to ask her why they didn't cite our papers, given their relevance?

  
Merc



Posts: 5
Joined: June 2013

(Permalink) Posted: June 28 2013,01:56   

Amazing...

John Mercer Pardon me? This was about engineering. You wrote, "Ask protein engineers how easy it is to redesign a protein to a genuinely new function." It starts with the 1999 JBC paper listed at the link Gary provided.

Biologic Institute In that paper you generate a null mutation, meaning a "loss of function" mutation. Not a new function. "As cellcell junctions are important in morphogenesis, we generated a null mutation in the murine Af6 locus to test the hypothesis that lack of AF-6 function would cause epithelial abnormalities....


John Mercer You are mistaken. I pointed you to the 1999 **JBC** paper. You described our Current Biology paper. The JBC paper is Engineering of the myosin-I? nucleotide-binding pocket to create selective sensitivity to N 6-modified ADP analogs, JBC 274:31373.

  
Occam's Aftershave



Posts: 1788
Joined: Feb. 2006

(Permalink) Posted: June 28 2013,08:33   

Quote (Merc @ June 28 2013,01:56)
Amazing...

John Mercer Pardon me? This was about engineering. You wrote, "Ask protein engineers how easy it is to redesign a protein to a genuinely new function." It starts with the 1999 JBC paper listed at the link Gary provided.

Biologic Institute In that paper you generate a null mutation, meaning a "loss of function" mutation. Not a new function. "As cellcell junctions are important in morphogenesis, we generated a null mutation in the murine Af6 locus to test the hypothesis that lack of AF-6 function would cause epithelial abnormalities....


John Mercer You are mistaken. I pointed you to the 1999 **JBC** paper. You described our Current Biology paper. The JBC paper is Engineering of the myosin-I? nucleotide-binding pocket to create selective sensitivity to N 6-modified ADP analogs, JBC 274:31373.

What do you expect? She's got her big fat mammary caught in the ringer, now has to resort to the usual Creationist tactic - lying - to save face.

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"Science is what got us to the humble place we’re at, and what hard-won progress we might realize comes from science, with ID completely flaccid, religious apologetics bitching from the sidelines." - Eigenstate at UD

  
Doc Bill



Posts: 1039
Joined: April 2007

(Permalink) Posted: June 28 2013,09:03   

How could it be a new function if they didn't grow wings and they're still monkeys?

Huh?

They're still fecking monkeys!

  
OgreMkV



Posts: 3654
Joined: Oct. 2009

(Permalink) Posted: June 28 2013,09:38   

Quote (Doc Bill @ June 27 2013,19:15)
I'd make a suitably inappropriate comment on their Facebook site but, of course, I'm blocked.

Yes, Gauger's silver banhammer came down on my head.

Shall I mention that you're blocked?  I suspect all of us will be soon enough.

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Ignored by those who can't provide evidence for their claims.

http://skepticink.com/smilodo....retreat

   
Dr.GH



Posts: 2138
Joined: May 2002

(Permalink) Posted: June 28 2013,21:03   

One observation regarding these online discussions- if there are "like" buttons we should use them. This might seem trivial, but market reserachers have found that they are significant in the opinions of neutral readers.

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"Science is the horse that pulls the cart of philosophy."

L. Susskind, 2004 "SMOLIN VS. SUSSKIND: THE ANTHROPIC PRINCIPLE"

   
Doc Bill



Posts: 1039
Joined: April 2007

(Permalink) Posted: June 28 2013,22:09   

Remember when Bio-Logic set all these Facebook rules?

No postings more than 100 words and no off-topic or uncivil or postings that contained letters between a-z.

I didn't say that Gauger "was" related to the troll king in the Hobbit, I said she "might have been."  Sheesh, picky picky!

  
Merc



Posts: 5
Joined: June 2013

(Permalink) Posted: July 01 2013,01:10   

Quote (Occam's Aftershave @ June 28 2013,08:33)
What do you expect? She's got her big fat mammary caught in the ringer, now has to resort to the usual Creationist tactic - lying - to save face.

It's a very stupid kind of lying, though. I could see her not knowing about the relevance of our work, as it was done to test mechanistic hypotheses, but for her to claim to be a "protein engineer" but not know about Shokat's work is just laughable.

And there's her inability to read Google Scholar lists of papers, abstracts, and figures, too...

  
Bob O'H



Posts: 2198
Joined: Oct. 2005

(Permalink) Posted: July 01 2013,03:18   

Quote
I didn't say that Gauger "was" related to the troll king in the Hobbit, I said she "might have been."  Sheesh, picky picky!

Hey, I liked the troll king.

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It is fun to dip into the various threads to watch cluelessness at work in the hands of the confident exponent. - Soapy Sam (so say we all)

   
Dr.GH



Posts: 2138
Joined: May 2002

(Permalink) Posted: July 01 2013,10:54   

Quote (Merc @ June 30 2013,23:10)
Quote (Occam's Aftershave @ June 28 2013,08:33)
What do you expect? She's got her big fat mammary caught in the ringer, now has to resort to the usual Creationist tactic - lying - to save face.

It's a very stupid kind of lying, though. I could see her not knowing about the relevance of our work, as it was done to test mechanistic hypotheses, but for her to claim to be a "protein engineer" but not know about Shokat's work is just laughable.

And there's her inability to read Google Scholar lists of papers, abstracts, and figures, too...

It is remarkable how little creationists care about lying, or being caught lying.

--------------
"Science is the horse that pulls the cart of philosophy."

L. Susskind, 2004 "SMOLIN VS. SUSSKIND: THE ANTHROPIC PRINCIPLE"

   
KevinB



Posts: 355
Joined: April 2013

(Permalink) Posted: July 01 2013,14:56   

Quote (Bob O'H @ July 01 2013,03:18)
Quote
I didn't say that Gauger "was" related to the troll king in the Hobbit, I said she "might have been." Sheesh, picky picky!

Hey, I liked the troll king.

Are you allowed to unlike the troll king without being eaten?

  
Doc Bill



Posts: 1039
Joined: April 2007

(Permalink) Posted: July 01 2013,15:14   

Quote (Bob O'H @ July 01 2013,03:18)
Quote
I didn't say that Gauger "was" related to the troll king in the Hobbit, I said she "might have been." Sheesh, picky picky!

Hey, I liked the troll king.

Rumor has it his daughter is available and sleepless in Seattle.

  
Glen Davidson



Posts: 1047
Joined: May 2006

(Permalink) Posted: July 02 2013,10:30   

Quote (Dr.GH @ July 01 2013,10:54)
Quote (Merc @ June 30 2013,23:10)
Quote (Occam's Aftershave @ June 28 2013,08:33)
What do you expect? She's got her big fat mammary caught in the ringer, now has to resort to the usual Creationist tactic - lying - to save face.

It's a very stupid kind of lying, though. I could see her not knowing about the relevance of our work, as it was done to test mechanistic hypotheses, but for her to claim to be a "protein engineer" but not know about Shokat's work is just laughable.

And there's her inability to read Google Scholar lists of papers, abstracts, and figures, too...

It is remarkable how little creationists care about lying, or being caught lying.

It's that transcendent morality.

Wonderful stuff.


Glen Davidson

--------------
http://tinyurl.com/mxaa3p....p

Nothing in biology makes sense except in the light of coincidence---ID philosophy

   
Henry J



Posts: 4809
Joined: Mar. 2005

(Permalink) Posted: July 03 2013,18:54   

Quote
It's that transcendent morality.

Wonderful stuff.

And, that's stuff that can't be derived from an algebraic equation!

  
The whole truth



Posts: 1554
Joined: Jan. 2012

(Permalink) Posted: Sep. 03 2016,10:28   

I wonder if the discotoot will close down the "Biologic Institute" now that Douglas Axe says:

"For me, the book, career-wise, marks a transition from doing a careful extended critique of Darwinism — I reached the point several years ago where I thought, I can’t think of anything else we can do; we’ve done all these careful experiments, we’ve published the results. We get people who bash them, but it’s only in blog articles. Nobody has gone in a lab and done work at the level we’ve done it to critique the work we’ve done. So, I feel like we’re beating a dead horse at some point, and I really want to shift gears."

http://www.wataugademocrat.com/mountai....fd.html

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Think not that I am come to send peace on earth: I came not to send peace, but a sword. - Jesus in Matthew 10:34

But those mine enemies, which would not that I should reign over them, bring hither, and slay them before me. -Jesus in Luke 19:27

   
NoName



Posts: 2721
Joined: Mar. 2013

(Permalink) Posted: Sep. 03 2016,10:34   

What, exactly, would shutting down the lab required?
Deleting the stock art picture file and the photoshopped file using it?

  
Glen Davidson



Posts: 1047
Joined: May 2006

(Permalink) Posted: Sep. 03 2016,12:22   

Quote (The whole truth @ Sep. 03 2016,10:28)
I wonder if the discotoot will close down the "Biologic Institute" now that Douglas Axe says:

"For me, the book, career-wise, marks a transition from doing a careful extended critique of Darwinism — I reached the point several years ago where I thought, I can’t think of anything else we can do; we’ve done all these careful experiments, we’ve published the results. We get people who bash them, but it’s only in blog articles. Nobody has gone in a lab and done work at the level we’ve done it to critique the work we’ve done. So, I feel like we’re beating a dead horse at some point, and I really want to shift gears."

http://www.wataugademocrat.com/mountai....fd.html

Oh come on Doug, you could do something even less connected with actual evolution and pretend that it means something.

Not much less connected to real evolutionary theory, but still somewhat less connected with the actual science.

Glen Davidson

--------------
http://tinyurl.com/mxaa3p....p

Nothing in biology makes sense except in the light of coincidence---ID philosophy

   
stevestory



Posts: 10402
Joined: Oct. 2005

(Permalink) Posted: Sep. 03 2016,12:35   

Quote (The whole truth @ Sep. 03 2016,11:28)
I wonder if the discotoot will close down the "Biologic Institute" now that Douglas Axe says:

"For me, the book, career-wise, marks a transition from doing a careful extended critique of Darwinism — I reached the point several years ago where I thought, I can’t think of anything else we can do; we’ve done all these careful experiments, we’ve published the results. We get people who bash them, but it’s only in blog articles. Nobody has gone in a lab and done work at the level we’ve done it to critique the work we’ve done. So, I feel like we’re beating a dead horse at some point, and I really want to shift gears."

http://www.wataugademocrat.com/mountai....fd.html

Quote
DA: What bothers me about the way the debate has played out is that both sides — the sides that I’m referring to here are the intelligent design proponents and the defenders of the orthodox Darwinian view — have tended to perpetuate the idea that this is basically a technical argument for scientists to hash out, and that the general public is to consume only the simplified explanations of what’s happening in that technical argument. That has bothered me for two reasons. One, because the establishment side, the orthodox Darwinian position, will always win if that’s how we frame the debate, because they outnumber us. There are far more people with Ph.D.s at top research facilities who disagree with me than the people who agree with me.
The other reason it bothers me is that I don’t fundamentally think that this is, at rock bottom, a technical issue. Common sense and very universal, simple reasoning actually can show you that Darwin’s story cannot be the true story.
So, I use the term common science to connect to common sense, but also to show that it’s not just that we have these intuitions, we actually have experienced observation models that we build as we go through life, beginning with early childhood, that really are scientific in nature. We don’t just pull these things out of thin air, we base them on our own observations and collective experience. They are really scientific in nature. That’s what I was aiming for with the term “common science.”


'I mean, just look at it. Like, it has to be made by somebody. I mean...just look at it.'

   
stevestory



Posts: 10402
Joined: Oct. 2005

(Permalink) Posted: Sep. 03 2016,12:37   

Quote
TM: It’s fairly late in the book before you actually begin writing about God, by name. Why is that?


Cuz I'm worn out from all this dishonesty and just don't care anymore?

   
Quack



Posts: 1961
Joined: May 2007

(Permalink) Posted: Sep. 04 2016,02:54   

Quote (OgreMkV @ June 27 2013,12:35)
 
Quote (Jim_Wynne @ June 27 2013,12:25)
   
Quote (Dr.GH @ June 27 2013,10:49)
You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Me too. �:p

Me 3.

I couldn't resist making my own comment (under my real name) although I think I am the least academic person in the game. 7 years in school, that's all! It may not be appropriate to praise yourself but just this once, I am proud of my 86 years old brain!

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Rocks have no biology.
              Robert Byers.

  
k.e..



Posts: 3896
Joined: May 2007

(Permalink) Posted: Sep. 04 2016,10:31   

Quote (Quack @ Sep. 04 2016,10:54)
Quote (OgreMkV @ June 27 2013,12:35)
   
Quote (Jim_Wynne @ June 27 2013,12:25)
   
Quote (Dr.GH @ June 27 2013,10:49)
You guys made me look, and then I had to make a comment... :D

https://www.facebook.com/Biologi....7268096

Me too. �:p

Me 3.

I couldn't resist making my own comment (under my real name) although I think I am the least academic person in the game. 7 years in school, that's all! It may not be appropriate to praise yourself but just this once, I am proud of my 86 years old brain!

Doesn't look like ur comment has seen the light of day yet.

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"I get a strong breeze from my monitor every time k.e. puts on his clown DaveTard suit" dogdidit
"ID is deader than Lenny Flanks granmaws dildo batteries" Erasmus
"I'm busy studying scientist level science papers" Galloping Gary Gaulin

  
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