|Wesley R. Elsberry
Joined: May 2002
Durston et al.:
For example, if we find that the Ribosomal S12 protein family has a Fit value of 379, we can use the equations presented thus far to predict that there are about 1049 different 121-residue sequences that could fall into the Ribsomal S12 family of proteins, resulting in an evolutionary search target of approximately 10^-106 percent of 121-residue sequence space.
Durston has a habit of thinking that what is in the protein databases comprises the universe of functional proteins. To get the sort of number he wants, he'd have to do an exhaustive assay to validate it. Instead, he "predicts" exactly the sort of tiny numbers he wants, and seems to be satisfied that he has demonstrated something. It's conceptually no better than the "cost of search" thing Dembski and Marks came up with a few years ago.
"You can't teach an old dogma new tricks." - Dorothy Parker