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 Topic: Evolutionary Computation, Stuff that drives AEs nuts < Next Oldest | Next Newest >
WebHopper

Posts: 7
Joined: Feb. 2017

 (Permalink) Posted: Feb. 11 2017,05:27

Wesley, if I understand you well the expected correct bases after mutation is

E = C + (u * (L - C) / K) - (u * C * (K - 1) / K)

where
C = number of correct bases
K = alphabet length
L = number of base pairs
u = mutation rate

I guess with "expected" E you refer to the mean. So if C=L we have

E = L (K + u - K u)/K

This is a linear law with respect to L if the other parameters are held constant. However, this does not match a Monte Carlo simulation, which shows that E is exponential with respect to L. So there must be some error in your calculation or I don't understand you well.

DiEb: Thanks for the link, I will look into this. Seems to be complicated however...

 405 replies since Mar. 17 2009,11:00 < Next Oldest | Next Newest >

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