Occam's Aftershave
Posts: 5287
Joined: Feb. 2006
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| Quote (Joe G @ Feb. 16 2014,08:01) | | There you have it- to falsify Intelligent Design all one has to do is demonstrate that natural selection can produce irreducibly complex biological systems. |
You lose Fatty.
| Quote | Evolution of Hormone-Receptor Complexity by Molecular Exploitation
Bridgham, Carroll, Thornton
Science, Science 7 April 2006: Vol. 312 no. 5770 pp. 97-101
Abstract: According to Darwinian theory, complexity evolves by a stepwise process of elaboration and optimization under natural selection. Biological systems composed of tightly integrated parts seem to challenge this view, because it is not obvious how any element's function can be selected for unless the partners with which it interacts are already present. Here we demonstrate how an integrated molecular system—the specific functional interaction between the steroid hormone aldosterone and its partner the mineralocorticoid receptor—evolved by a stepwise Darwinian process. Using ancestral gene resurrection, we show that, long before the hormone evolved, the receptor's affinity for aldosterone was present as a structural by-product of its partnership with chemically similar, more ancient ligands. Introducing two amino acid changes into the ancestral sequence recapitulates the evolution of present-day receptor specificity. Our results indicate that tight interactions can evolve by molecular exploitation—recruitment of an older molecule, previously constrained for a different role, into a new functional complex.
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Now what Chubs - a Joe Gallien chin counting contest?
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"CO2 can't re-emit any trapped heat unless all the molecules point the right way"
"All the evidence supports Creation baraminology"
"If it required a mind, planning and design, it isn't materialistic."
"Jews and Christians are Muslims."
- Joke "Sharon" Gallien, world's dumbest YEC.
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